The Clinical Predictors of and Vaccine Protection Against Severe Influenza Infection in Children.

The most significant risk factors associated with severe influenza infection were an age under 2 years, comorbidities (cardiovascular, neuropsychological, and respiratory diseases), patchy infiltrates or effusion shown on chest X-rays, and bacterial coinfections. The incidence rate of severe disease was significantly lower in those who had received influenza vaccines and PCVs. This article is protected by copyright. All rights reserved.