Chronic opioid use is associated with early biologic discontinuation in inflammatory bowel disease.
Christian RhudyCourtney L PerryMichael SingletonJeffery TalbertTerrence A BarrettPublished in: Alimentary pharmacology & therapeutics (2021)
Chronic opioid use is associated with increased hazard of biologic discontinuation in inflammatory bowel disease. Symptoms of opioid withdrawal may mimic IBD flares thereby leading providers to inappropriately switch biologic therapies and compromise disease control.