Comparative analysis of decidual and peripheral immune cells and immune-checkpoint molecules during pregnancy in wild-type and PACAP-deficient mice.

Adrienn LajkoMatyas MeggyesBalazs Daniel FulopNoemi GedeDora ReglodiLaszlo Szereday

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2018)

The only remarkable finding is the recruitment of Gal-9+ Th cells to the decidua promoting local immune homeostasis in PACAP KO mice, which nevertheless cannot explain the reduced fertility observed in these mice.

Keyphrases

wild type
induced apoptosis
high fat diet induced
type diabetes
oxidative stress
insulin resistance
young adults
cell death