Novel imaging biomarkers for mapping the impact of mild mitochondrial uncoupling in the outer retina in vivo.
Bruce A BerkowitzHailey K OldsCollin RichardsJoydip JoyTilman RosalesRobert H PodolskyKaren Lins ChildersWilliam Brad HubbardPatrick G SullivanShasha GaoYichao LiHaohua QianRobin RobertsPublished in: PloS one (2020)
The present results raise the possibility of non-invasively evaluating the mouse rod mitochondrial energy ecosystem using new DNP-assisted OCT and MRI in vivo assays.