Atrium-specific ion channels in the zebrafish-A role of IKACh in atrial repolarization.

Mark Alexander SkarsfeldtS H BomholtzP R LundegaardA Lopez-IzquierdoM Tristani-FirouziB H Bentzen

Published in: Acta physiologica (Oxford, England) (2018)

We demonstrate that the acetylcholine-activated inward-rectifying current (IKACh ) current plays a major role in the zebrafish atrium and that the zebrafish could potentially be a cost-effective and reliable model for pharmacological testing of atrium-specific IKACh modulating compounds.

Keyphrases

vena cava
inferior vena cava
pulmonary artery
catheter ablation
left atrial appendage
atrial fibrillation
coronary artery
signaling pathway
pulmonary hypertension
pulmonary embolism
left atrial