Circulating Brain-enriched MicroRNAs for detection and discrimination of idiopathic and genetic Parkinson's disease.

Stylianos RavanidisAnastasia BougeaNikolaos PapagiannakisMatina ManiatiChristos KorosAthina-Maria SimitsiMaria BoziIoanna PachiMaria StamelouGeorge P ParaskevasElisabeth KapakiMarina MoraitouHelen MichelakakisLeonidas StefanisEpaminondas Doxakis

Published in: Movement disorders : official journal of the Movement Disorder Society (2019)

The study provides a group of brain-enriched miRNAs that may be used for the detection and differentiation of PD subtypes. It has also identified the molecular pathways deregulated in PD. © 2019 International Parkinson and Movement Disorder Society.

Keyphrases

resting state
white matter
loop mediated isothermal amplification
real time pcr
label free
functional connectivity
cerebral ischemia
gene expression
blood brain barrier
dna methylation