The Role of Cyclin d1 in Radiotherapy Resistance of Advance Stage Nasopharyngeal Carcinoma: A Systematic Review.

Achmad Chusnu Romdhoni Arya Satya Rajanagara Chabib Fachry Albab Langgeng Agung Waskito Idznika Nurannisa Wibowo Mohamad Yunus Mohd Razif

Published in: Asian Pacific journal of cancer prevention : APJCP (2024)

In conclusion, Cyclin D1 has a strong correlation with radiation resistance; downregulation of the protein increases radiosensitivity, while overexpression of the protein promotes radioresistance.

Keyphrases

cell cycle
cell proliferation
protein protein
early stage
amino acid
radiation induced
radiation therapy
binding protein
signaling pathway
cell cycle arrest
transcription factor
small molecule
rectal cancer
cancer stem cells
pi k akt