Changes in antimicrobial resistance and outcomes of health care-associated infections.
Mehtap AydınEmel AzakHüseyin BilginSirin MenekseAli AsanHabibe Tülin Elmaslar MertZerrin YulugkuralLutfiye Nilsun AltunalÇiğdem Ataman HatipoğluGunay Tuncer ErtemElif Sargın AltunokMelike Hamiyet DemirkayaSevil Alkan ÇevikerFethiye AkgulZeynep MemisPetek KonyaAlpay AzapGule AydinDerya KorkmazZehra Çagla KarakoçDerya YaparFaruk KarakeciliOzgur GunalSiran KeskeMahir KapmazCigdem KaderAslıhan DemirelÖnder ErgönülPublished in: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology (2021)
To describe the change in the epidemiology of health care-associated infections (HAI), resistance and predictors of fatality we conducted a nationwide study in 24 hospitals between 2015 and 2018. The 30-day fatality rate was 22% in 2015 and increased to 25% in 2018. In BSI, a significant increasing trend was observed for Candida and Enterococcus. The highest rate of 30-day fatality was detected among the patients with pneumonia (32%). In pneumonia, Pseudomonas infections increased in 2018. Colistin resistance increased and significantly associated with 30-day fatality in Pseudomonas infections. Among S. aureus methicillin, resistance increased from 31 to 41%.