Immune Checkpoint Inhibitor-induced Reinvigoration of Tumor-infiltrating CD8+ T Cells is Determined by Their Differentiation Status in Glioblastoma.
Junsik ParkMinsuk KwonKyung Hwan KimSeon-Hui HongSeok-Gu KangJu Hyung MoonSu-Hyung ParkJong Hee ChangEui-Cheol ShinPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)
In primary GBM, the differentiation status of CD8+ TILs determines their reinvigoration ability upon ICI treatment.