A crosstalk between gut and brain in sepsis-induced cognitive decline.
Vijayasree V GiridharanJaqueline S GenerosoLeonardo LenceGabriela CandiottoEmílio StreckFabricia PetronilhoAnilkumar PillaiTarek SharsharFelipe Dal-PizzolTatiana BarichelloPublished in: Journal of neuroinflammation (2022)
Since several pharmacological studies have failed to prevent cognitive impairment in sepsis survivors, a better understanding of the function of glial cells and gut microbiota can provide new avenues for treating sepsis patients.
Keyphrases
- cognitive decline
- acute kidney injury
- septic shock
- intensive care unit
- cognitive impairment
- end stage renal disease
- mild cognitive impairment
- induced apoptosis
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- cell cycle arrest
- high glucose
- cell death
- neuropathic pain
- resting state
- cell proliferation
- diabetic rats
- multiple sclerosis
- signaling pathway
- blood brain barrier
- spinal cord injury
- case control
- subarachnoid hemorrhage
- stress induced