Recombinant Culicoides obsoletus complex allergens stimulate antigen-specific T cells of insect bite hypersensitive Shetland ponies in vitro.

Chantal MeulenbroeksNathalie M A van der MeideTon WillemseVictor P M G RuttenEdwin Tijhaar

Published in: Veterinary dermatology (2015)

The recombinant C. obsoletus complex allergens can stimulate antigen-specific Th1 and IL10 producing Treg cells and are therefore promising candidates for the immunotherapy of IBH.

Keyphrases

induced apoptosis
cell cycle arrest
cell free
endoplasmic reticulum stress
cell death
oxidative stress
signaling pathway
cell proliferation
zika virus
allergic rhinitis