Quantification of cell-free circulating mitochondrial DNA copy number variation in hepatocellular carcinoma.

Burhanettin Yalçınkaya Didem Taştekin Fatih Guzelbulut Muslum Akgoz Sadrettin Pençe

Published in: Revista da Associacao Medica Brasileira (1992) (2022)

Circulating mtDNA copy number was decreased in hepatocellular carcinoma patients in comparison with healthy individuals, and we suggest that it can be used as a noninvasive biomarker for hepatocellular carcinoma diagnosis in the future.

Keyphrases

copy number
mitochondrial dna
cell free
genome wide
end stage renal disease
dna methylation
chronic kidney disease
newly diagnosed
prognostic factors
current status
circulating tumor cells
clinical evaluation