Evaluating programmed death-ligand 1 (PD-L1) in head and neck squamous cell carcinoma: concordance between the 22C3 PharmDx assay and the SP263 assay on whole sections from a multicentre study.

Bruna CerbelliIlaria GirolamiAlbino EccherLeopoldo CostarelliSilvia TaccognaRenzo ScialpiMaria BenevoloTeresa LucantePiero Luigi AlòFrancesca StellaMaria Gemma PignataroGuido FaddaGiuseppe PerroneGiulia D'AmatiMaurizio Martini

Published in: Histopathology (2021)

Two different assays (the 22C3 PharmDx assay and SP263 assay) for PD-L1 in HNSCC showed high agreement. These data suggest that these two assays are interchangeable in the selection of patients with HNSCC for immunotherapy.

Keyphrases

high throughput
single cell
big data
data analysis