Anti-β2-glycoprotein I and anti-phosphatidylserine/prothrombin antibodies exert similar pro-thrombotic effects in peripheral blood monocytes and endothelial cells.

Adriana Cifù Rossana DomenisC PistisF CurcioMartina Fabris

Published in: Auto- immunity highlights (2019)

Our data support the significant and independent role of aPS/PT in the pathogenesis of the thrombotic events in APS patients, possibly adding new light to the therapeutic management of cases characterized by the sole presence of aPS/PT IgG antibodies.

Keyphrases

peripheral blood
endothelial cells
end stage renal disease
ejection fraction
newly diagnosed
peritoneal dialysis
prognostic factors
dendritic cells
big data
machine learning
immune response
deep learning
anti inflammatory
data analysis