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Capsaicin attenuates Porphyromonas gingivalis-suppressed osteogenesis of periodontal ligament stem cells via regulating mitochondrial function and activating PI3K/AKT/mTOR pathway.

Weijia WangZhiyan ZhouTian DingSusu FengHongrui LiuMengmeng LiuShaohua Ge
Published in: Journal of periodontal research (2024)
Capsaicin increases osteogenesis of PDLSCs under inflammation and reduces alveolar bone resorption in mouse experimental periodontitis.
Keyphrases
  • stem cells
  • bone regeneration
  • bone loss
  • oxidative stress
  • bone mineral density
  • signaling pathway
  • soft tissue
  • postmenopausal women
  • bone marrow