The influence of the gastrointestinal microbiome on colorectal metastasis: a narrative review.

Aine Stakelum Alexandra M Zaborowski Danielle Collins Des C Winter

Published in: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland (2020)

The invasive pathways utilized by bacteria and how they may be manipulated by tumour cells for migration and metastasis are presented and the potential of the intestinal microbiome as a therapeutic target in colorectal carcinogenesis and metastasis is detailed here.

Keyphrases

induced apoptosis
cell cycle arrest
risk assessment
cell proliferation
endoplasmic reticulum stress
oxidative stress
signaling pathway
human health