Gut Microbiome Signatures of Risk and Prodromal Markers of Parkinson Disease.

Sebastian Heinzel Velma T E AhoUlrike SuenkelAnna-Katharina von ThalerClaudia SchulteChristian DeuschleLars PaulinSari HantunenKathrin BrockmanGerhard W EschweilerWalter MaetzlerDaniela BergPetri AuvinenFilip Scheperjans

Published in: Annals of neurology (2021)

Several risk and prodromal markers of PD are associated with gut microbiome composition. However, the impact of the gut microbiome on PD risk and potential microbiome-dependent subtypes in the prodrome of PD need further investigation based on prospective clinical and (multi)omics data in incident PD cases. ANN NEUROL 2021;90:E1-E12.

Keyphrases

parkinson disease
deep brain stimulation
cardiovascular disease
gene expression
genome wide
electronic health record
big data
risk assessment
neural network