Validation of the movement disorder society criteria for the diagnosis of 4-repeat tauopathies.
Gesine RespondekMax-Joseph GrimmInes PiotThomas ArzbergerYaroslau ComptaElisabet EnglundLeslie W FergusonEllen GelpiSigrun RoeberArmin GieseMurray GrossmanDavid J IrwinWassillios G MeissnerChrister NilssonAlexander Y PantelyatAlex RajputJohn C van SwietenClaire TroakesGünter U Höglingernull nullPublished in: Movement disorders : official journal of the Movement Disorder Society (2019)
The new diagnostic category "probable 4R-tauopathy" showed high specificity and may be suitable for the recruitment of patients with progressive supranuclear palsy and corticobasal degeneration into therapeutic trials targeting 4R-tauopathy. The low sensitivity underpins the need for diagnostic biomarkers. © 2019 International Parkinson and Movement Disorder Society.