Relationship between time-to-isolation and freeze duration: Computational modeling of dosing for Arctic Front Advance and Arctic Front Advance Pro cryoballoons.

This model predicted a minimum duration of cryoballoon ablation (TTINV ) to obtain a transmural lesion when acute TTI of the PV was observed (TTIED ). Consequently, the model is a useful tool for characterizing CBA dosing, which may guide future cryoablation dosing strategies.