Neutrophil-dendritic cell interaction plays an important role in live attenuated Leishmania vaccine induced immunity.

Parna BhattacharyaNevien IsmailAnkit SaxenaSreenivas GannavaramRanadhir DeyTimur OljuskinAdovi AkueKazuyo TakedaJames YuSubir KarmakarPradeep K DagurJohn Philip McCoyHira L Nakhasi

Published in: PLoS neglected tropical diseases (2022)

Collectively, LdCen-/- containing neutrophils phagocytized by DC markedly influence the phenotype and antigen presenting capacity of DCs early on and thus play an immune-regulatory role in shaping vaccine induced host protective response.

Keyphrases

dendritic cells
high glucose
diabetic rats
drug induced
oxidative stress
regulatory t cells