Reproductive risk factors in breast cancer and genetic hormonal pathways: a gene-environment interaction in the MCC-Spain project.

Trinidad Dierssen-SotosCamilo Palazuelos-CalderónJosé-Juan Jiménez-MoleónNuria AragonésJone M AltzibarGemma Castaño-VinyalsVicente Martín-SanchezInés Gómez-AceboMarcela GuevaraAdonina TardónBeatriz Pérez-GómezPilar AmianoVictor MorenoAntonio J MolinaJéssica Alonso-MoleroConchi Moreno-IribasManolis KogevinasMarina PollánJavier Llorca

Published in: BMC cancer (2018)

The number of deliveries had a dose-response protective effect on breast cancer; women carrying C allele in rs2229712 did not benefit from this protective effect.

Keyphrases

risk factors
polycystic ovary syndrome
genome wide
copy number
breast cancer risk
quality improvement
dna methylation
type diabetes
gene expression
metabolic syndrome
genome wide identification