Multi-omics gut microbiome signatures in obese women: role of diet and uncontrolled eating behavior.
Monica BaroneSilvia GarelliSimone RampelliAlessandro AgostiniSilke MatysikFederica D'AmicoSabrina KrautbauerRoberta MazzaNicola SalituroFlaminia FanelliPatricia IozzoYolanda SanzMarco CandelaPatrizia BrigidiUberto PagottoSilvia TurroniPublished in: BMC medicine (2022)
By finding peculiar gut microbiome profiles associated with eating patterns, we laid the foundation for elucidating gut-brain axis communication in the obese phenotype. Subject to confirmation of the hypotheses herein generated, our work could help guide the design of microbiome-based precision interventions, aimed at rewiring microbial networks to support a healthy diet-microbiome-gut-brain axis, thus counteracting obesity and related complications.
Keyphrases
- weight loss
- bariatric surgery
- physical activity
- resting state
- white matter
- weight gain
- polycystic ovary syndrome
- functional connectivity
- microbial community
- cerebral ischemia
- obese patients
- type diabetes
- single cell
- genome wide
- adipose tissue
- insulin resistance
- pregnancy outcomes
- cervical cancer screening
- body mass index