Halide Perovskite Nanocrystals with Enhanced Water Stability for Upconversion Imaging in a Living Cell.
Pavel M TalianovOleksii O PeltekMikhail MasharinSoslan KhubezhovMikhail A BaranovAudrius DrabavičiusAlexander S TiminLev E ZelenkovAnatoly P PushkarevSergey V MakarovMikhail V ZyuzinPublished in: The journal of physical chemistry letters (2021)
Halide perovskite nanomaterials are widely used in optoelectronics and photonics due to their outstanding luminescent properties, whereas their strong multiphoton absorption makes them prospective for bioimaging. Nonetheless, instability of perovskites in aqueous solutions is an important limitation that prevents their application in biology and medicine. Here, we demonstrate fluorescence and upconversion imaging in living cells by employing CsPbBr3 nanocrystals (NCs) that show an improved water-resistance (at least for 24 h) after their coating as individual particles with various silica-based shells. The obtained phTEOS-TMOS@CsPbBr3 NCs possess high quality, which we confirm with high-resolution transmission and scanning transmission electron microscopy, X-ray diffraction analysis, Fourier-transform infrared and energy-dispersive X-ray spectroscopies, as well as with fluorescence optical microscopy. The developed platform can make the halide perovskite NCs suitable for various bioimaging applications.
Keyphrases
- high resolution
- energy transfer
- solar cells
- living cells
- electron microscopy
- quantum dots
- fluorescent probe
- single molecule
- room temperature
- high efficiency
- mass spectrometry
- high speed
- photodynamic therapy
- ionic liquid
- single cell
- sensitive detection
- high throughput
- mesenchymal stem cells
- tandem mass spectrometry
- gas chromatography
- magnetic resonance
- cell therapy
- magnetic resonance imaging
- mouse model
- bone marrow
- liquid chromatography