Results of a multicenter universal newborn screening program for sickle cell disease in Italy: A call to action.

Raffaella ColombattiMaddalena MartellaLaura CattaneoGiampietro ViolaAnita CappellariChiara BergamoSilvia AzzenaSara SchiavonEugenio BaraldiBeatrice Dalla BarbaUrsula TrafojerPaola CortiMarzia UggeriPaolo Emilio TagliabueChiara ZorloniMichela BracchiAndrea BiondiGiuseppe BassoNicoletta MaseraLaura Sainati

Published in: Pediatric blood & cancer (2019)

Our results demonstrate the feasibility of a multicentric NBS program for SCD, give information on HbS epidemiology in two Northern Italian Areas, and support previous European recommendation for a universal NBS program for SCD in Italy: a high incidence of patients and carriers has been detected, with a high percentage of Caucasian carriers, impossible to identify in a targeted NBS.

Keyphrases

sickle cell disease
quality improvement
end stage renal disease
risk factors
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
healthcare
health information
cancer therapy
patient reported outcomes
drug delivery
african american
social media