Preserved thenar muscles in non-ambulant Duchenne muscular dystrophy patients.

Karin J Naarding Kevin R Keene Aashley S D Sardjoe Mishre Thom T J Veeger Nienke M van de VeldeArina J PrinsJedrzej Burakiewicz Jan J G M Verschuuren Menno van der Holst Erik H Niks Hermien E Kan

Published in: Journal of cachexia, sarcopenia and muscle (2021)

Low thenar FF, increased T2water , correlation of muscle size with strength and function, and the decrease in strength and function over 1 year indicate that the thenar muscles are a valuable and quantifiable target for therapy in later stages of DMD. Further studies are needed to relate these data to the loss of a clinically meaningful milestone.

Keyphrases

duchenne muscular dystrophy
end stage renal disease
chronic kidney disease
ejection fraction
newly diagnosed
skeletal muscle
muscular dystrophy
stem cells
big data
patient reported outcomes
machine learning
deep learning
artificial intelligence