Impact of heart failure drug therapy on rates of gastrointestinal bleeding in LVAD recipients: An INTERMACS analysis.

Douglas L JenningsLauren K TrubyAudrey J LittlefieldAlana M CiolekDylan MarshallRashmi JainVeli K Topkara

Published in: The International journal of artificial organs (2021)

Despite recent reports, ACEi/ARB, MRA, Amio, and digoxin use does not appear to be associated with GIB during LVAD support. The heightened risk seen in those on loop diuretics may reflect venous congestion in these patients, while antiplatelet effects of PDE5 could drive the higher risk of GIB.

Keyphrases

heart failure
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors
peritoneal dialysis
adverse drug
left ventricular
magnetic resonance
atrial fibrillation
computed tomography
mesenchymal stem cells
patient reported
cell therapy
acute heart failure