Assessment of Antibiotic De-escalation by Spectrum Score in Patients With Nosocomial Pneumonia: A Single-Center, Retrospective Cohort Study.

Daniel T IlgesDavid J RitchieTamara KrekelElizabeth A NeunerNicholas HamptonMarin H KollefScott Micek

Published in: Open forum infectious diseases (2021)

De-escalation and NDE resulted in similar rates of 30-day treatment failure; however, DE was associated with fewer antibiotic days, episodes of C difficile infection, and days of hospitalization.

Keyphrases

open label
clinical trial
intensive care unit
acinetobacter baumannii
cystic fibrosis
acute respiratory distress syndrome
community acquired pneumonia
pseudomonas aeruginosa
replacement therapy
extracorporeal membrane oxygenation
smoking cessation
mechanical ventilation