The alkylaminoalkanethiosulfuric acids exhibit in-vitro antileishmanial activity against Leishmania (Viannia) braziliensis: a new perspective for use of these schistosomicidal agents.
Gabriane Nascimento PorcinoLuciana Maria Ribeiro AntinarelliAna Carolina Ribeiro Gomes MaiaPriscila Faria-PintoAlessandro Taunay-RodriguesPaulo Marcos Zech CoelhoDavid Lee NelsonMarcus Luiz Oliveira PenidoElaine Soares CoimbraEveline Gomes VasconcelosPublished in: The Journal of pharmacy and pharmacology (2019)
In this previously unpublished study of trypanosomatids, it is shown that AAATs could also exhibit selective antileishmanial activity, a new possibility to be investigated in oral treatment of leishmaniasis.