Cognitive Performance as a Function of MAPT Haplotype: A Prospective Longitudinal Study of an Essential Tremor Cohort.

Ali GhanemDiane S BerryKurt FarrellStephanie CosentinoJohn F CraryElan D Louis

Published in: Tremor and other hyperkinetic movements (New York, N.Y.) (2023)

This study found no evidence of cognitive differences between individuals with and without the MAPT H1 haplotype. Our work provides a valuable foundation for future work to expand our knowledge of the genetic drivers of cognitive impairment in ET.

Keyphrases

cognitive impairment
healthcare
deep brain stimulation
genome wide
parkinson disease
current status
copy number
gene expression
dna methylation