Dose and timing of injections for effective cyclosporine A pretreatment before renal ischemia reperfusion in mice.

Sandrine LemoineBruno PillotLionel AugeulMaud RabeyrinAnnie VarennesGabrielle NormandDelphine BaetzMichel OvizeLaurent Juillard

Published in: PloS one (2017)

Our results suggest that the protection afforded by CsA is likely limited by its availability. The dose and timing of the injections are therefore crucial to ensure that the treatment is effective, but these findings may prove challenging to apply in practice.

Keyphrases

platelet rich plasma
ultrasound guided
primary care
healthcare
high fat diet induced
adipose tissue
insulin resistance
skeletal muscle
replacement therapy