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Design, in silico study, synthesis and evaluation of hybrid pyrazole substituted 1,3,5-triazine derivatives for antimalarial activity.

Pritom BorgohainAnshul ShakyaSurajit Kumar GhoshNeelutpal GogoiSaurav Jyoti PatgiriIpsita Pal BhowmickDibya Ranjan BhattacharyyaUdaya Pratap SinghHans Raj Bhat
Published in: Experimental parasitology (2024)
Among the ten derivatives, compound 7J has considerable potential as an antimalarial agent, making it a viable contender for further refinement in the realm of pharmaceutical exploration, with the aim of mitigating the global malaria load.
Keyphrases
  • molecular docking
  • plasmodium falciparum
  • structure activity relationship
  • risk assessment
  • climate change