IgM and IgA augmented autoantibody signatures improve early-stage detection of colorectal cancer prior to nodal and distant spread.

Md Saiful Islam RoneyCatharine LanaganYong Hua ShengKaren LawlerChristopher SchmidtNam-Trung NguyenJakob BegunGregor Stefan Kijanka

Published in: Clinical & translational immunology (2021)

IgM AAbs are associated with early-stage colorectal cancer. Combining IgG, IgM and IgA AAbs is a novel strategy to improve early diagnosis of cancers.

Keyphrases

early stage
lymph node
sentinel lymph node
genome wide
neoadjuvant chemotherapy
dna methylation
radiation therapy
young adults
rectal cancer
locally advanced