Silver Nanoparticles Conjugate Attenuates Highly Active Antiretroviral Therapy-Induced Hippocampal Nissl Substance and Cognitive Deficits in Diabetic Rats.
Sodiq Kolawole LawalSamuel Oluwaseun OlojedeAyobami DareOluwaseun Samuel FaborodeEdwin Coleridge Stephen NaiduCarmen Olivia RennieOnyemaechi Okpara AzuPublished in: Journal of diabetes research (2021)
Administration of HAART to diabetic rats aggravates the complications of diabetes and promotes neurotoxic effects on the experimental rats, while HAART-loaded silver nanoparticle (HAART-AgNP) alleviates diabetes-induced neurotoxicity.
Keyphrases
- diabetic rats
- oxidative stress
- silver nanoparticles
- hiv infected patients
- antiretroviral therapy
- type diabetes
- cardiovascular disease
- glycemic control
- human immunodeficiency virus
- drug delivery
- gold nanoparticles
- hiv infected
- risk factors
- metabolic syndrome
- adipose tissue
- hiv aids
- hiv positive
- hepatitis c virus
- weight loss
- south africa
- brain injury
- wound healing
- temporal lobe epilepsy