Kdm6a Deficiency Activates Inflammatory Pathways, Promotes M2 Macrophage Polarization, and Causes Bladder Cancer in Cooperation with p53 Dysfunction.
Kohei KobatakeKen-Ichiro IkedaYuichiro NakataNorimasa YamasakiTakeshi UedaAkinori KanaiKazuhiro SentaniYasuyuki SeraTetsutaro HayashiMiho KoizumiYoshihiko MiyakawaToshiya InabaYusuke SotomaruOsamu KaminumaTatsuo IchinoheZen-Ichiro HondaWataru YasuiShigeo HoriePeter C BlackAkio MatsubaraHiroaki HondaPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
Our findings provide insights into multistep carcinogenic processes of bladder cancer and suggest molecular targeted therapeutic approaches for patients with bladder cancer with KDM6A dysfunction.