Role of IL-18-transformed CD274-expressing eosinophils in promoting airway obstruction in experimental asthma.

Anil MishraDewan MajidHemanth Kumar KandikattuChandra Sekhar YadavalliSathisha Upparahalli Venkateshaiah

Published in: Allergy (2021)

We demonstrate that IL-18 is critical for inducing asthma pathogenesis, and neutralization of CD274 is a potential immunotherapeutic strategy for asthma.

Keyphrases

chronic obstructive pulmonary disease
lung function
allergic rhinitis
nk cells
air pollution