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Nicotinic alpha-7 acetylcholine receptor deficiency exacerbates hepatic inflammation and fibrosis in a mouse model of non-alcoholic steatohepatitis.

Kumi KimuraYuka InabaHitoshi WatanabeToshiya MatsukawaMichihiro MatsumotoHiroshi Inoue
Published in: Journal of diabetes investigation (2018)
The results of this study suggest that α7nAchR deficiency exacerbates hepatic inflammation and fibrosis in a diet-induced mouse model of NASH.
Keyphrases
  • mouse model
  • oxidative stress
  • liver fibrosis
  • replacement therapy
  • liver injury
  • binding protein
  • smoking cessation