Macrophage GSK3β-deficiency inhibits the progression of hepatocellular carcinoma and enhances the sensitivity of anti-PD1 immunotherapy.

Guangshun SunHanyuan LiuJie ZhaoJinyu ZhangTian HuangGuoqiang SunSiqi ZhaoZihao ZhangHengsong CaoDawei RongXiangyi KongQinghua JiLi LiuXuehao WangWeiwei Tang Yongxiang Xia

Published in: Journal for immunotherapy of cancer (2023)

in PBMC can noninvasively predict anti-PD1 sensitivity in HCC patients, which provides novel strategies to predict anti-PD1 sensitivity, increase anti-PD1 therapeutic effect, and bring new hope for HCC patients.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
prognostic factors
signaling pathway
patient reported outcomes
cell proliferation
patient reported
pi k akt