Identification of risk in cutaneous melanoma patients: Prognostic and predictive markers.
David M HyamsRobert W CookAntonio C BuzaidPublished in: Journal of surgical oncology (2018)
New therapeutic modalities for melanoma promise benefit in selected individuals. Efficacy appears greater in patients with lower tumor burden, suggesting an important role for risk-stratified surveillance. Robust predictive markers might permit optimization of agent to patient, while low-risk prognostic markers might guide more conservative management. This review evaluates protein, gene, and multiplexed marker panels that may contribute to better risk assessment and improved management of patients with cutaneous melanoma.
Keyphrases
- risk assessment
- end stage renal disease
- skin cancer
- newly diagnosed
- ejection fraction
- public health
- chronic kidney disease
- peritoneal dialysis
- case report
- genome wide
- gene expression
- single cell
- risk factors
- machine learning
- patient reported outcomes
- big data
- basal cell carcinoma
- climate change
- artificial intelligence
- patient reported