Acute kidney injury in severe alcohol-associated hepatitis treated with anakinra plus zinc or prednisone.
Kavish R PatidarWanzhu F TuThomas Gerard CotterDouglas A SimonettoAmon AsgharpourMuhammad Y JanQing TangYunpeng YuYang LiMoyinoluwa TaiwoPrashanth Thevkar NageshSrinivasan DasarathyPatrick S KamathCraig J McClainNaga ChalasaniGyongyi SzaboRamon BatallerMack C MitchellWajahat Z MehalLaura E NagyVijay H ShahSamer GawriehArun J Sanyalnull nullPublished in: Hepatology (Baltimore, Md.) (2024)
AKI occurred more frequently and was more severe in participants treated with A+Z. A+Z-treated participants with AKI had higher urine-neutrophil-gelatinase-associated lipocalin, suggesting that A+Z maybe nephrotoxic in patients with severe alcohol-associated hepatitis.