Diffusion weighted imaging in patients with rectal cancer: Comparison between Gaussian and non-Gaussian models.
Georgios C ManikisKostas MariasDoenja M J LambregtsKaterina NikiforakiMiriam M van HeeswijkFrans C H BakersRegina G H Beets-TanNickolas PapanikolaouPublished in: PloS one (2017)
No single diffusion model evaluated herein could accurately describe rectal tumours. These findings probably can be explained on the basis of increased tumour heterogeneity, where areas with high vascularity could be fitted better with bi-exponential models, and areas with necrosis would mostly follow mono-exponential behavior.