Multiple Retinal Anomalies in Wfs1-Deficient Mice.

Arleta Waszczykowska Agnieszka Zmyslowska Marcin Braun Marilin IvaskSulev KoksPiotr JurowskiWojciech Mlynarski

Published in: Diagnostics (Basel, Switzerland) (2020)

Wfs1KO mice retina with mutation in exon 8 present similar clinical features as patients with WFS in the form of reduced retinal thickness and neurodegeneration of the optic nerve. The presence of proliferative retinopathy observed in Wfs1KO mice requires further investigation.

Keyphrases

optic nerve
optical coherence tomography
diabetic retinopathy
high fat diet induced
type diabetes
insulin resistance
metabolic syndrome
skeletal muscle