Low-intensity pulsed ultrasound therapy suppresses coronary adventitial inflammatory changes and hyperconstricting responses after coronary stent implantation in pigs in vivo.
Tasuku WatanabeYasuharu MatsumotoKensuke NishimiyaTomohiko ShindoHirokazu AmamizuJun SugisawaSatoshi TsuchiyaKoichi SatoSusumu MorosawaKazuma OhyamaTomomi Watanabe-AsakaMoyuru HayashiYoshiko KawaiJun TakahashiSatoshi YasudaHiroaki ShimokawaPublished in: PloS one (2021)
These results suggest that our non-invasive LIPUS therapy is useful to treat coronary functional abnormalities caused by coronary adventitial inflammation, indicating its potential for the novel and safe therapeutic approach of coronary artery disease.
Keyphrases
- coronary artery disease
- coronary artery
- percutaneous coronary intervention
- cardiovascular events
- coronary artery bypass grafting
- oxidative stress
- magnetic resonance imaging
- aortic stenosis
- signaling pathway
- cardiovascular disease
- stem cells
- type diabetes
- aortic valve
- left ventricular
- ultrasound guided
- atrial fibrillation
- cell therapy
- replacement therapy
- contrast enhanced ultrasound