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Differential adipokine receptor expression on circulating leukocyte subsets in lean and obese children.

Genoveva KeustermansLaila B van der HeijdenBerlinda BoerRianne ScholmanRoos NuboerGerard PasterkampBerent PrakkenWilco de JagerEric KalkhovenArieke J JanseHenk S Schipper
Published in: PloS one (2017)
First, the distinct adipokine receptor profiles of circulating leukocyte subsets may partly explain the differential impact of adipokines on leukocyte subsets. Second, the similarities in adipokine receptor expression profiles between obese children and normal weight controls suggest that adipokine signaling in childhood obesity is primarily modulated by circulating adipokine levels, instead of adipokine receptor expression.
Keyphrases
  • peripheral blood
  • weight loss
  • young adults
  • metabolic syndrome
  • adipose tissue
  • type diabetes
  • body mass index
  • physical activity
  • obese patients
  • binding protein
  • weight gain
  • bone mineral density