Association of the Leukocyte Immunoglobulin-like Receptor A3 Gene With Neutrophil Activation and Disease Susceptibility in Adult-Onset Still's Disease.
Mengyan WangMengru LiuJinchao JiaHui ShiJialin TengHonglei LiuYue SunXiaobing ChengJunna YeYutong SuHuihui ChiTingting LiuZhihong WangLiyan WanJianfen MengYuning MaChengde YangQiong-Yi HuPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2021)
Our study provides the first evidence that functional LILRA3 is a novel genetic risk factor for the development of AOSD and that functional LIR-A3 may play a pathogenic role by inducing formation of NETs.