Anti-Cytosolic 5'-Nucleotidase 1A in the Diagnosis of Patients with Suspected Idiopathic Inflammatory Myopathies: An Italian Real-Life, Single-Centre Retrospective Study.

Brunetta PorcelliMiriana d'AlessandroLatika GuptaSilvia GrazziniNila VolpiMaria Romana BacarelliFederica GinanneschiGiovanni BiasiFrancesca BellisaiMarta FabbroniDavid Bennett Claudia Fabiani Claudia Fabiani Elena BargagliBruno FredianiEdoardo Conticini

Published in: Biomedicines (2023)

Our study suggests excellent concordance between LIA and ELISA for detecting anti-cN1A antibodies. LIA may be a rapid and useful adjunct, and it could even replace ELISA for cN1A assay. However, the high prevalence of diseases other than IBM in our cohort of anti-cN1A-positive patients did not allow us to consider anti-cN1A antibodies as a specific biomarker for IBM.

Keyphrases

lymph node metastasis
end stage renal disease
chronic kidney disease
newly diagnosed
prognostic factors
peritoneal dialysis
high throughput