Colopathy Associated with Pentosan Polysulfate Use.

Emily H JungWei ZhengRyan J WeissNamita E MathewBenjamin I MeyerAzhar NizamHeba IskandarNieraj Jain

Published in: medRxiv : the preprint server for health sciences (2023)

We describe a strong association between PPS use and a clinical diagnosis of IBD and/or IBS. Histopathologic findings suggest a novel drug-associated colopathy, with some subjects requiring colectomy for dysplasia.

Keyphrases

ulcerative colitis
emergency department