Blood utilization and characteristics of patients treated with chronic transfusion therapy in a large cohort of Brazilian patients with sickle cell disease.
Shannon KellyAndré Rolim BelisárioDaniela O Werneck RodriguesAnna B F Carneiro-ProiettiThelma T GonçalezPaula LoureiroMiriam V Flor-ParkClaudia MaximoRosimere Afonso MotaCarla Luana DinardoDonald J BrambillaLiliana PreissEster Cerdeira SabinoBrian Custernull nullPublished in: Transfusion (2020)
Red blood cell transfusion was common in Brazilian SCD patients, with utilization driven by CTT. Transfusion reactions were not common; however, alloimmunization and iron overload were frequent among those on CTT, highlighting the need for novel clinical strategies to mitigate these risks.