MicroRNA regulating stanniocalcin-1 is a metastasis and dissemination promoting factor in glioblastoma.
Junichi SakataTakashi SasayamaKazuhiro TanakaHiroaki NagashimaMitsutoshi NakadaHirotomo TanakaNaoya HashimotoNaoki KagawaManabu KinoshitaSatoshi NakamizoMasahiro MaeyamaMasamitsu NishiharaKohkichi HosodaEiji KohmuraPublished in: Journal of neuro-oncology (2019)
STC1 may be a novel metastasis/metastatic dissemination promoting factor regulated by several miRs in GBM. Because STC1 is a secreted glycoprotein and functions via the autocrine/paracrine signals, inhibiting STC1 signal may become a novel therapeutic strategy for GBM.