Parapneumonic effusions related to Streptococcus pneumoniae : serotype and disease severity trends from 2006 to 2018 in Bristol, UK.

Catherine HyamsDavid T ArnoldRobyn HeathZahin Amin-ChowdhuryDavid HettleGabriella RuffinoPaul NorthCharli GrimesNorman K FryPhilip WilliamsRobert ChallenLeon DanonO Martin WilliamsShamez LadhaniAdam FinnNick Maskell

Published in: BMJ open respiratory research (2023)

Pneumococcal infection continues to cause severe disease despite the introduction of PCVs. The predominance of serotype 1 and 3 in this adult UK cohort is in keeping with previous studies in paediatric and non-UK studies. Rising non-PCV serotype disease and limited impact of PCV13 on cases caused by serotypes 1 and 3 offset the reductions in adult pneumococcal parapneumonic effusion disease burden observed following the introduction of the childhood PCV7 programme.

Keyphrases

dengue virus
intensive care unit
klebsiella pneumoniae
emergency department
escherichia coli
early onset
study protocol
multidrug resistant
young adults