O- and N-Glycosylation of Serum Immunoglobulin A is Associated with IgA Nephropathy and Glomerular Function.
Viktoria DotzAlessia ViscontiHannah J Lomax-BrowneFlorent ClercAgnes L Hipgrave EderveenNicholas R Medjeral-ThomasH Terence CookMatthew C PickeringManfred WuhrerMario FalchiPublished in: Journal of the American Society of Nephrology : JASN (2021)
Our high-resolution data suggest that IgA O- and N-glycopeptides are promising targets for future investigations on the pathophysiology of IgAN and as potential noninvasive biomarkers for disease prediction and deteriorating kidney function.